エス・ピー・ジーテクノ株式会社SPG Technology Co.,Ltd

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Ⅰ Foods

No Language Title Key words
Ⅰ-(1) JPN Application of membrane emulsification method to food emulsion Food W/O, direct membrane emulsification method, monodisperse, practical use with hydrophilic membrane, 7 modules, scale-up, fat percentage margarine
Ⅰ-(2) JPN Production of micro W/O emulsions from food raw materials using hydrophobized SPG membranes Food W/O, direct membrane emulsification, high speed mini kit, monodisperse, PGCR
Ⅰ-(3) JPN Preparation of monodisperse O/W food emulsion by membrane emulsification method Food O/W, Pre-emulsified emulsion dispersion phase, direct membrane emulsification method, monodisperse, high speed mini kit, corn oil, emulsifier glycerin fatty acid ester, PGCR
Ⅰ-(4) JPN Method for preparing W/O food emulsion using hydrophilic membrane Food W/O, Direct Membrane Emulsification, High Speed Mini Kit, Internal Pressure Micro Kit, Hydrophobicization of Hydrophilic Membrane, PGCR
Ⅰ-(5) JPN Simple method for preparing monodisperse edible oil O/W emulsion Food O/W, Direct Membrane Emulsification, High Speed Mini Kit, Monodisperse, Continuous Phase Fill in Dispersed Phase Tank, Corn Oil, PGCR, SDS, Triton X-100
Ⅰ-(6) JPN Preparation conditions for O/W food emulsion by membrane emulsification method Foods O/W, W/O, direct membrane emulsification, high speed mini kit, monodisperse, corn oil, emulsifier, sucrose fatty acid ester, PGCR, sodium caseinate, SDS, hydrophobic emulsifier sorbitan fatty acid ester, continuous phase circulation rate, Dispersed phase permeation flow velocity, emulsifier concentration, critical pressure
Ⅰ-(7) JPN Preparation conditions for W/O food emulsion by membrane emulsification method Food W/O, direct membrane emulsification method, internal pressure microkit, monodisperse, hydrophobicization of hydrophilic membrane with continuous phase oil, corn oil, PGCR, dispersed phase salt concentration, continuous phase circulation rate, dispersed phase permeation flow velocity, emulsifier concentration

Ⅱ Cosmetics

No Language Title Key words
Ⅱ-(1) JPN Application of SPG membrane emulsification method to cosmetics Cosmetics O/W, W/O, monodisperse, direct membrane emulsification, high speed mini kit, safety of nonionic surfactant, HLB, hydrophilic, HCO-5, HCO-50, methylphenylpolysiloxane, silicone
Ⅱ-(2) JPN Stability of cosmetic emulsions by membrane emulsification technology Cosmetics O/W, monodisperse, direct membrane emulsification, high speed mini kit, low concentration surfactant, critical pressure, HLB, SDS, polyoxyethylene alkyl ether, polyoxyethylene sorbitan fatty acid ester, decaglycerin fatty acid ester, kerosine, Liquid paraffin, soybean oil, continuous phase
Ⅱ-(3) JPN Stability and sustained release properties of protein-encapsulating W/O/W emulsions Cosmetics W/O/W, monodisperse, primary homogenizer, secondary direct membrane emulsification, protein, magnesium ascorbic acid, paraoxybenzene, squalane, decaglycerin pentaoleate, hexaglycerin condensed ricinoleate, external aqueous polyvinyl alcohol, monolaurin Decaglycerin acid, parapen, butyl alcohol

Ⅲ Microcapsule / Fine particle preparation

No Language Title Key words
Ⅲ-(1) JPN Preparation of microcapsules by in-situ polymerization method using emulsification method with porous glass Microcapsules, O/W, monodisperse, direct membrane emulsification, high speed mini kit, polymerization, ethyl oleate, styrene monomer, divinylbenzene, dodecylbenzenesulfonic acid, calcium phosphate, gum arabic
Ⅲ-(2) JPN Preparation of functional resin microspheres Resin microspheres, O/W, monodisperse, direct membrane emulsification, internal pressure microkit, polymerization, styrene monomer, divinylbenzene, butyl alcohol, isoamyl alcohol, nhexyl alcohol, 2-2 azobis, isobutyronitrile, AIBN
Ⅲ-(3) JPN Synthesis of calcium alginate monodisperse microspheres Calcium alginate microspheres, W/O, W/O/W, monodisperse, direct membrane emulsification, polymerization, hydrophobicization, octadecyltrichlorosilane, trimethylchlorosilane, sodium alginate, hexane, span80, aqueous calcium chloride solution
Ⅲ-(4) JPN Fine particle synthesis by membrane emulsification method Polymer beads O/W, monodisperse, direct membrane emulsification, high speed mini kit, polymerization, styrene monomer, divinylbenzene, toluene, dodecane, azobisisobutyronitrile (AIBN), sodium dodecylbenzenesulfonate, calcium phosphate
Ⅲ-(5) JPN Application of membrane emulsification method to suspension polymerization Microspheres, O/W, monodisperse, direct membrane emulsification, polymerization, styrene monomer, divinylbenzene, toluene, benzoyl peroxide, benzoyl peroxide, lauryl alcohol, PVA, SDS
Ⅲ-(6) JPN Preparation of monodisperse SiO2 fine particles by membrane emulsification method and particle formation process Silica gel, W/O, monodisperse, direct membrane emulsification, sodium silicate, ammonium bicarbonate, kerosene, polyglycerin condensed ricinolic acid ester, PGCR, sol, hydrogel, xerogel
Ⅲ-(7) JPN Preparation of monoisperse particle size microcapsules Microspheres, W/O, monodisperse, direct membrane emulsification, polymerization, polyamide membranes, polyion complex membranes, microcapsules, sodium alginate, albumin microspheres, span80, polylactic acid microspheres, polylactic acid-glycolic acid copolymers, PLGA, dichloromethane
Ⅲ-(8) JPN Production of monoisperse polymer fine particles by membrane emulsification method Polymer, fine particles, O/W, monodisperse, direct membrane emulsification, polymerization, multiple modules, scale-up, divinylbenzene, benzoyl peroxide BPO, sodium dodecylbenzene sulfonate DBS, long-term use, regeneration, reproducibility
Ⅲ-(9) JPN Synthesis of monodisperse large particles using both SPG membrane emulsification method and swelling method Polymer, fine particles, O / W, monodisperse, direct membrane emulsification, seed polymerization, styrene monomer, divinylbenzene, hexadecane, benzoyl peroxide (benzoyl peroxide), seed emulsion, swollen emulsion, benzene, toluene, dichlorobenzene, hexanol , Octanol, PVA, PVP, CMC
Ⅲ-(10) JPN Charging characteristics of the toner particles prepared by SPG membrane emulsification method Toner fine particles, O / W, monodisperse, direct membrane emulsification method, polymerization, chemical toner, styrene monomer, divinylbenzene, carbon black, dichloromethane, azobisdimethylvaleronitrile (ADVN), azobisisobutyronitrile (AIBN), SDS, PVA, in-liquid drying method, solvent volatilization, chargeability
Ⅲ-(11) JPN Formation mechanism of monodisperse spherical silica particles by membrane emulsification method Silica, fine particles, W/O, W/O/W, monodisperse, direct membrane emulsification method, sodium silicate, ammonium hydrogen carbonate, kerosene, polyglycerin condensed ricinolic acid ester, PGCR
Ⅲ-(12) JPN Preparation of HEMA containing monoisperse fine particles with a combination of SPG membrane emulsification method and a droplet swelling method Microspheres, O/W, monodisperse, direct membrane emulsification, styrene monomer, divinylbenzene, hexadecane, polymerization, benzoyl peroxide BPO, PVA aqueous solution, SDS, aqueous phase inhibitor, hydroquinone, hydroxymethacrylate (HEMA), methyl methacrylate (MMA), membrane wet
Ⅲ-(13) JPN Features and Possibilities of Fillers for High Performance Liquid Chromatography of Organic Polymers by Membrane Emulsification Polymer, fine particles, O/W, monodisperse, direct membrane emulsification method, internal pressure type microkit, polymerization, styrene monomer, divinylbenzene, toluene, two-step swelling polymerization method, column packing material
Ⅲ-(14) JPN Production of monodisperse solder fine particles by membrane emulsification method Solder, particles, O/W, W/O, monodisperse, direct membrane emulsification, ultra-low melting point metal, hydrophilic membrane, hydrophobic membrane, SDS, TGCR, kerosene, lead stearate, paraffin stearate solution, metal soap

Ⅳ Mechanization / Device

No Language Title Key words
Ⅳ-(1) JPN Plant engineering in the membrane emulsification method SPG module, disk type, micro capacity, tube type, pipe type, small capacity, large capacity, membrane area, membrane emulsification plant, micro kit, mini kit, pilot, maintenance, cleaning, regeneration, ultrasonic cleaning, energy saving
Ⅳ-(2) JPN Development of syringe type small membrane emulsification device SPG module, small size, disposable, syringe type, flow control, pressure control, stirrer, internal pressure type micro kit, syringe pump, DDS, cancer drug, W/O/W, small amount, lipiodol, monodisperse
Ⅳ-(3) JPN Rapid preparation of W/O/W emulsion and improvement of membrane emulsification device SPG module, disposable, small size, syringe type, flow control, stirrer, internal pressure type micro kit, syringe pump, W/O/W, monodisperse, epirubicin hydrochloride, lipiodol, polyglycerin condensed ricinoleic acid ester, PGCR, polyoxyethylene curing Castor oil, HCO-40, HCO-60, encapsulation rate, spectrophotometer

Ⅴ Basic examination

No Language Title Key words
Ⅴ-(1) JPN Oil phase permeation rate through SPG membrane O/W, direct membrane emulsification method, monodisperse, high-speed mini kit, oil phase permeation rate, paraffin, kerosene, kerosene, Tween20, circulation flow velocity, oil phase viscosity, temperature
Ⅴ-(2) JPN Preparation of monodisperse W/O emulsion by membrane emulsification method W/O, direct membrane emulsification, monodisperse, hydrophobic, octadecyltrichlorosilane, trimethylchlorosilane, monodisperse, dispersed phase sodium chloride aqueous solution, continuous phase kerosene, surfactant polyglycerin condensed ricinolic acid ester, PGCR, pure water, Solubilization, polydispersion, dispersed phase salt concentration, in-pipe flow velocity
Ⅴ-(3) JPN Preparation of W/O/W emulsion by membrane emulsification method W/O/W, direct membrane emulsification method, monodisperse, potassium chloride KCl aqueous solution, oil phase soybean oil, surfactant polyglycerin condensed ricinolic acid ester PGCR, sodium chloride, NaCl aqueous solution, Pluronic F68, homogenizer, osmotic pressure, oil Phase transmission, expansion, contraction
Ⅴ-(4) JPN Emulsion particle design driven by osmotic pressure W/O/W, direct membrane emulsification method, monodisperse, W/O, hydrophobic membrane, sodium chloride aqueous solution, kerosene, kerosene, PGCR, external aqueous phase pure water, osmotic pressure, driving force, water movement, oil phase permeation , Swelling, contraction
Ⅴ-(5) JPN Viscosity characteristics of monodisperse emulsion O/W, direct membrane emulsification, monodisperse, high-speed mini kit, kerosine, kerosene, SDS, agglomeration, W/O, sodium chloride aqueous solution, continuous phase PGCR kerosene solution, viscosity, slip rate, Newtonian fluid, non-Newtonian fluid, Pseudoplastic flow, plastic flow
Ⅴ-(6) JPN The influence of osmotic pressure in the preparation of monodisperse W/O/W emulsion W/O/W, direct membrane emulsification method, monodisperse, 100% encapsulation rate, W/O, homogenizer, osmotic pressure, potassium chloride aqueous solution, soybean oil, PGCR, polyoxyethylene sorbitan monolaurate tween20, leakage rate, surfactant Activator concentration
Ⅴ-(7) JPN Electrochemical considerations for the stability of monodisperse O/W emulsions O/W, direct membrane emulsification method, monodisperse, high-speed mini kit, kerosene, kerosene, SDS, electrolyte, zeta potential, adsorption, interfacial strength, stability, DLVO theory, setting kinetics
Ⅴ-(8) JPN Kinetic study of oil phase permeation of water in W/O emulsions W/O, W/O/W, direct membrane emulsification, monodisperse, oil phase permeation of water, osmotic pressure, W/O emulsion mixing, expansion, shrinkage, surfactant concentration
Ⅴ-(9) JPN Examination of the interface state of emulsion particles using a membrane emulsified emulsion O/W, permeation membrane emulsification method (preliminary emulsification method), premix, oil phase corn oil, hexaglycerin condensed ricinoleic acid ester, continuous phase glycerin fatty acid ester, sucrose fatty acid ester, HLB10, creaming, zeta potential, flow potential method , Ester potential, electrostatic repulsion
Ⅴ-(10) JPN Stability of emulsion prepared by membrane emulsification method O/W, direct membrane emulsification method, monodisperse, external pressure microkit, zeta potential, DLVO theory, aggregation, total potential energy, electrostatic repulsion potential, attractive potential, SDS, adsorption, interfacial tension
Ⅴ-(11) JPN Mechanical strength and fracture of emulsion particles O/W, direct membrane emulsification method, monodisperse, oil phase kerosene, carbon tetrachloride, CCl4, specific gravity, SDS, sodium alginate AlgNa, shear force, shear stress
Ⅴ-(12) JPN Engineering evaluation of emulsion capsule production by membrane emulsification method / Comparison with conventional methods in particle size distribution, encapsulation rate and internal aqueous phase filling rate W/O/W, direct membrane emulsification, monodispersity, encapsulation rate, 100% encapsulation, ammonium ferric citrate, atomic absorption spectrophotometer, soybean oil, PGCR
Ⅴ-(13) JPN Composition and emulsification properties of polyglycerin condensed ricinoleic acid type surfactant Nonionic surfactant, polyglycerin condensed ricinoleic acid ester PGCR, component purification, high performance liquid chromatograph, polymerization

Ⅵ Medical / Pharmaceutical

No Language Title Key words
Ⅵ-(1) JPN Preparation of new lipiodol emulsion containing water-soluble cancer drug W/O/W, direct membrane emulsification, monodisperse, SPG disc, hepatic artery embolization TAE, antitumor effect, DDS, SMANCS, epirubicin hydrochloride, glucose, lipiodol, PGCR, ultrasonic emulsification, Proxummer 188, Glucose
Ⅵ-(2) JPN Application of W/O/W emulsion to pediatric oral medicine W/O/W, direct membrane emulsification, monodisperse, antipyretic sulpyrine, Bayer, suppository, pediatric, side effects, oral administration, glucose, soybean oil, PGCR, ultrasonic homogenizer, external aqueous phase glucose, Pluronic F68, animal experiments , Preclinical studies, human clinical studies, administration, blood levels, flavors
Ⅵ-(3) JPN Preparation of monodisperse W/O/W emulsion containing water-soluble cancer drug W/O/W, direct membrane emulsification, monodisperse, DDS, SPG disc, hepatocellular carcinoma embolic chemotherapy TACE, cancer drug, epirubicin hydrochloride, carboplatin, lipiodol, PGCR, pulluronic F68, polyoxyethylene hydrogenated castor oil HCO-60, Clinical trials, viscous emulsions, medicinal properties, osmotic pressure, swelling
Ⅵ-(4) JPN Application and possibility of membrane emulsification method to DDS W/O/W, direct membrane emulsification, monodisperse, DDS, clinical trials, liposomes, lipid microspheres, encapsulation rate, tumor cells, endocytosis, macrophages, immunosurveillance cells
Ⅵ-(5) JPN Excellent properties of W/O/W emulsion prepared by membrane emulsification method in hepatocellular carcinoma diagnosis W/O/W, O/W, direct membrane emulsification, monodisperse, DDS, clinical trials, tumor accumulation, hepatocellular carcinoma detection, diagnosis, epirubicin hydrochloride, oil phase lipiodol, external aqueous phase saline, surface activity Agent, tumor lipiodol deposits, washout
Ⅵ-(6) JPN Preparation and sustained release characteristics of HGF-containing emulsified preparations using SPG membranes W/O/W, direct membrane emulsification, monodisperse, DDS, hepatocyte growth factor HGF, hepatocyte growth factor, liver regeneration promoting therapy, bioactive substances, in vivo, in vivo aqueous phase lycobinant, phosphate buffer Liquid, tween80, serum albumin, dextran sulfate, lipiodol, rat, portal vein administration, blood test
Ⅵ-(7) JPN Stability and sustained drug release characteristics of W/O/W emulsified products W/O/W, direct membrane emulsification, monodisperse, internal pressure SPG module, epirubicin hydrochloride, lactose, lipiodol, PGCR, HCO-40, epirubicin concentration, refrigerated storage, encapsulation rate, supernatant volume, aging, stability , Sustained release leakage, absorbance
Ⅵ-(8) JPN Drug sustained release control and rheological changes of W/O/W emulsified preparations using osmotic pressure W/O/W, direct membrane emulsification, monodisperse, DDS, in-hospital preparation, hepatocellular carcinoma treatment, intraarterial injection, sustained drug release, shelf life, stability, epirubicin hydrochloride, lactose, lipiodol, PGCR, HCO-40, Saline, HCO-60, osmotic pressure, swelling, encapsulation rate, filling rate, close packing, fluidity
Ⅵ-(9) JPN Liver arterial infusion therapy for primary liver cancer with W/O/W emulsified DDS preparation-examination of long-term observation cases W/O/W, direct membrane embolization, monodisperse, DDS, primary liver cancer, hepatocellular carcinoma, intraarterial infusion, hepatic artery embolization TAE, tumor accumulation, iodized poppyseed oil (IPSO), lipiodol, lymphangiography , Smanx, suspension, epirubicin hydrochloride, deposition, clinical trials
Ⅵ-(10) JPN Dynamics of ionized poppy-seed oil (IPSO) microdroplets administered into the hepatic artery W/O/W, direct membrane emulsification, monodisperse, DDS, hepatocellular carcinoma, iodized poppyseed oil (IPSO), lipiodol, particles, intraarterial injection, lung deposition, pulmonary embolism, animal experiments, rabbits, liver, lungs, spleen , Extraction, TACE
Ⅵ-(11) JPN Effect of particle size in the biodistribution of iodinated poppy oil administered in hepatic artery W/O/W, direct membrane embolization, monodisperse, DDS, hepatocellular carcinoma, iodized poppyseed oil (IPSO), lipiodol, oil particles, intraarterial injection, pulmonary veins, pulmonary deposits, pulmonary embolism, animal experiments, rabbits Hepatic artery, O / W, liver, lung, kidney, spleen, excision
Ⅵ-(12) JPN Cardiotoxicity reduction effect by emulsification of anthracycline cancer drug epirubicin W/O/W, direct membrane emulsification, monodisperse, internal pressure SPG module, syringe pump, DDS, cancer drug, epirubicin epirubicin, adriamycin adriamycin, cardiotoxicity, lipiodol, intraarterial injection, animal experiments, rats, blood concentration, liver , Heart, excision, lipid peroxide level, creatine phosphokinase, CPK
Ⅵ-(13) JPN Biodistribution after hepatic arterial infusion administration of emulsions having a monoisperse particle size with iodinated poppy seed oil W/O/W, O/W, direct membrane emulsification, monodisperse, DDS, hepatocellular carcinoma, iodized poppyseed oil (IPSO), intraarterial injection, animal experiments, rabbits, saline, HCO-60, small, large , IPSO particles, oil particles, pulmonary deposits, pulmonary embolism, liver, lungs, spleen, excision, blood concentration
Ⅵ-(14) JPN Leakage and hydrolysis of cancer drugs irinotecan hydrochloride in the W/O/W emulsion W/O/W, preliminary experiment, mechanical emulsification method, cancer agent, irinotecan hydrochloride CPT-11, soybean oil, PGCR, sucrose erucate, microcapsules, cellulose derivative, hydroxypropylmethylcellulose acetate succinate, polylactic acid, oil Phase Ethyl acetate, dichloromethane, in-liquid drying method, encapsulation amount
Ⅵ-(15) ENG Arterial-Injection Chemotherapy for Hepatocellular Carcinoma Using Monodispersed Poppy-Seed Oil Microdroplets Containing Fine Aqueous Vesicles of Epirubicin W/O/W、DDS、the membrane-emulsification、thin round plates、emulsion、monodispersed、HCC、arterial-injection therapy、epirubicin、Iodized poppy-seed oil (IPSO) 、side effects、tetraglycerine-condensated ricinoleate、poloxamer-188
Ⅵ-(16) ENG Size of Lipid Microdroplets Effects Results of Hepatic Arterial Chemotherapy with an cancer drug in Water-in-Oil-inWater Emulsion to Hepatocellular Carcinoma W/O/W、DDS、hepatocellular carcinoma (HCC)、membrane emulsification、emulsion、iodinated poppy seed oil (IPSO)、stability、microdroplets、chemo therapy、injected、the hepatic artery、the 30 um diameter of IPSO microdroplets、 rabbits、Epirubicin hydrochloride、Lipiodol、Patient demographics